Proxmox configuration question for 2 NVME Machines

[xalyy]

Hello! I would like to ask for some advice here what type of installation and configuration setup do you guys recommend for this 2 systems:

1. System
2xE5-2670V2
64GB RAM
1x1TB NVME SSD and 1x128GB SATA SSD for Proxmox

2. System
2xE5-2696V2
128GB RAM
2x1TB NVME SSD and 1x128GB SATA SSD for Proxmox

Im planning to run about 50-100 Linux VM's on these machines and looking for a recommended configuration about what storage type to chose, what disk format to use for the VM's or in general what to look for to get the maximum performance out of everything. The NVME SSD's are running through PCIE Adaptor cards. Possibly I would use RAID 0 for the second system since the 2 NVME SSD's.
Thanks for the help!

 

[LnxBil]

Do you want to have a production system on those systems? If yes, your only choice is to use ZFS with replication enabled to have an almost high available system.

 

[xalyy]

Do you want to have a production system on those systems? If yes, your only choice is to use ZFS with replication enabled to have an almost high available system.

Well not really just some application running on them that has to load once. It only consumes CPU and RAM.