Making some progress, the one remaining VM is running a task at 5:00am each morning and that is the exact time the kernel panics. The VM is CentOS 7 but with a 5.13 kernel. The task does a bunch of data backups. I have just run each of them in order and the host panics when doing an rsync between the two 3TB drives inside the guest. The two drives are mounted by the host as LVM datastores, the guest has a volume /dev/vdb in one and /dev/vdc in the other both formatted as xfs.
This would suggest to me that under a high(ish) IO load on the host when running 5.11, something isn't happy.
This would suggest to me that under a high(ish) IO load on the host when running 5.11, something isn't happy.