I have read many of the tuning guides and tried most of what they have suggested but it didn't make a significant difference.. Only thing I haven't thrown in the mix (because I don't have a spare one) is an SSD as a log (ZIL) and read cache (L2ARC)..That's not true, you just haven't tuned ZFS properly. Google for ZFS tuning, there are lots of parameters to adjust depending on what you are trying to achieve. Storage systems are always a trade of between data integrity and speed. ZFS defaults to data integrity.
I use GlusterFS with it's built-in NFS server for Citrix XenServer, and get pretty good speeds. I'm currently replicating two storage nodes, but it can be expanded to three or more as well.
noatime,nodiratime,nobarrier,logbufs=8,logbsize=256k ...means (256k)
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