4 x 16TB - Better setup?

[FuriousRage]

Hi, im on my way to pick up my new home server hardware.
Going to have 4 HDD:s á 16TB each. (And 2x1TB nvme for boot / pve / other stuff?)
What would be the most sensible setup for the 16 TB drives, Atleast 10TB is going to be needed by either a NAS or something like seafile/nextcloud.
I was thinking in the lines of Raidz2, According to https://wintelguy.com/zfs-calc.pl i would get roughly 24TB drive space for VM:s and data with Raidz2

EDIT: the drives are 7200 RPM, the raid is so not everything is lost in case of a drive failure. I will have atleast one 10TB storage box @ hetzner for backup "off site".

 

[FuriousRage]

Use only Flashmedia usable for datacenter usage.

Where did flash come from? Or do you mean the m.2 nvme as flash?

 

[LnxBil]

Or do you mean the m.2 nvme as flash?

If those are enterprise grade SSD, use them for this. Otherwise buy new SSDs