FYI Ive been running on the ASUS Creator Wi-Fi for a few months how. I originally had the MSI Carbon and that board wasn't playing nice with IOMMU groups if I recall and had to compile the 5G NIC driver. Shortly after I was experimenting with the MSI board the ASUS board came on the market and I immediately returned the MSI board for the ASUS. The ASUS was a little unstable at first, crashed a couple times but ASUS to their credit just started bombing out BIOS updates for the next few months and it's now been rock solid for me:
265k CPU
NVIDIA GPU
ARC310 GPU
3 NVMEs
16i Storage Card
192GB DDR 5
N5 Case
12 HDDs
Coral m.2
All running very well. No issues
Truenas
Bunch of Portainer VMs
Kubernetes VMs
Backup VMs
Win11 VM
Various transcoding containers, cameras with passthrough of all kinds of devices; GPUs, m.2, coral iGPU NVIDIA remote windows gaming server...