I had no issues with an older XPEnology and the based loader. And there are no issues with unsing ESXi 8.0 Update 3.
But after updating the loader of XPEnology to a newer version the same issue happens. I had also these issues with XCP-NG that I tested earlier. Regarding Proxmox I tested with the newest available igb driver but had no success.
With the other onboard NIC on my Supermicro X10SLM-F board, an i217 using the e1000e driver there are no issues.
Because it looks like that not all i210 NICs have this issue I come to the conclusion that this issue is relatetd to a correlation of the X10 board, the new linux kernel and the igb driver which doesn't exist with older linux kernels.