Just made an account to report that I was having a seemingly very similar issue myself. Fresh Proxmox install, fresh VM of PopOs(Latest) with GPU passthrough of a NVIDIA RTX 2070 Ti. Default storage settings. Between 5min-16hr or so after startup the guest either reboots or completely freezes and doesn't respond to the host web UI shutdown or restart requests. The "STOP" button in the web panel does seem to work to shut it down, though. Disabling iothread does not seem to have any effect.
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