Images bigger size, fewer # of images compared to smaller sizes, higher # of images

[proxminent]

Hi!
Bigger size, fewer number of images compared to smaller sizes, higher number of images makes a performance difference?
In my case, I have a VM with two disk images, 1x32Gb + 1x4Ttb (DMS archive filesystem)
What is better and / or more secure?

PVE on 2 nodes with ZFS ....
Many Thanks !