There are A LOT of ways you can set this up. The Proxmox Administration Guide is your friend here. You certainly can do what you asked. You can separate Proxmox into basically two parts - the system and the storage. You then have flexibility in both of these, and really need to read about the pros and cons of each. Personally I went with a ZFS install in UEFI mode for the system on a single drive. I have a local (on the same metal) zpool in a mirrored 2 drive storage for my VM's/Containers (this is overkill for a home lab in my opinion). I attach to a NAS for the high volume (media/photos) stuff and backups of my VMs/containers (which is why the local mirrored storage is over kill - restoring a VM from a backup is very easy and the downtime required in a home is no big deal). After a bit of research, you may find your current plan is not the best. The system is based on Debian and pretty small, so you may want to install on something other than one of your SSDs (a regular hard drive for example) and set your 4 SSDs into a Raid config (for either one big volume or one with some redundancy for data protection).
One recommendation I would make if this is a just a home install (not used for business) is to not worry about protecting the system installation with any sort of raid. It is very easy to bring that back from complete loss with just a couple of strategic backups. My second recommendation is to learn about ZFS...it is quite amazing in what you can do with it.
Good luck!