Can i configure the DRBD or Fire Replication trough Web Interface ?

No, you cannot, I'm afraid. Webinterface configurations is only available for Ceph (clustered storage) and ZFS (local storage).

For Proxmox VE with DRBD 9 linbit Maintains a storage Plugin and should be asked regarding all questions to it:
https://docs.linbit.com/docs/users-guide-9.0/#ch-proxmox

There's also a external Storage plugin for NetApp, but currently no Webinterface integration and no direct support from us.