What I would do in your situation:
1. since you have a limited amount of ssd's, I'd install PVE on disks 0+1. yes that means a 2.4TB of raw disk for such a small use but the alternative will be more impactful.
2. "Slow" Pool: disks 2-13, striped mirror
3. "Fast" Pool: disks 18-23, striped mirror...