ZFS Pool Degraded & Drive Removed

[phongwashere]

Does this mean that the drive is dead? Could it be a glitch where I can just reseat the drive? This is currently running some mission critical VMs. We have the environment backed up to our Synology NFS storage, but would like to know what would be the best way to resolve these errors. We've only had the server up for about 6 months.

 

[leesteken]

Could it be a glitch where I can just reseat the drive?

It could be. It could also be an experiment with PCI(e) passthrough and the second NVMe was part of the same IOMMU group. It could also be a cooling issues or some other kind of hardware failure. It's hard to say without more data. Run journalctl -b 0 and scroll through it (using the arrow keys) to maybe find a reason why the drive disappeared?
PS: Posting output of commands (like zpool status VMpool) in CODE-tags instead of screenshots is much more readable (and searchable) for people (even without visual impairments).