QCOW2 on ZFS, but over NFS?

So you don't have a pve cluster with zfs replication between running ?
Not sure how this is relevent. But since you ask; no, I don't believe in clusters for Proxmox :)

HA is IMHO grossly overrated and in many setups it causes more downtime because of added complexity than it actually saves uptime.
Especially considering how rock solid a good server with ZFS mirrors and redundant PSU runs.
Even for single nodes, software has always be a way higher risk factor than hardware for me. To be honest, in all these decades running servers, I never had a single downtime because of hardware. I had once a PSU failing, once DELL VRTX CMC, 3 APC batteries and maybe 10 disks failing, not a single failure that actually caused downtime (besides the two times fiber line cutting from construction and once power outage for 3 hours, but these would have happened with a cluster too).
 
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