This is not the default query you would ask just in the forums. To answer this properly, best to contact a proxmox partner for a tailored setup. Information is just not enough to answer properly. Your money bounds would also be very important. CEPH in general is more expensive than just buying one HA-SAN solution with e.g. dedicated storage paths. For CEPH you would need a good network infrastructure, which is also costly.
I will try to address the easier questions with some assumptions:
Minimum and recommended number of nodes for a stable cluster
3 is the minimum number of nodes for a Proxmox VE cluster. The stable aspect is AFAIK in the number of maximum nodes, which depends heavily on the used network and latency between the nodes. If all are in one DC, it should be better, yet you will not have problems up to 15 nodes. Number has be odd.
5 would be the minimum number of nodes for a CEPH cluster.
CPU sizing per node (Intel/AMD generation, core count, overcommit guidance)
AMD has generally more NUMA nodes, but higher core counts, better performance and higher number of PCIe lanes, so in general better performance on paper. More NUMA nodes may need some pinning and optimization. You will also have licensing problems for you VMs if you e.g. run something like an Oracle database on EPYC with Standard Edition licensing.
Depending on the mininum frequency for each core, the number of cores varies. So if you require fast cores, you can only have e.g. 16 core EPYC and have for example the requirement for 256 real cores /512 threads), 256 / 16 / 2 = 9 nodes. Assuming 512 threads is sufficient for the number of vCPUs. Without any real utilization, no one can plan.
Storage design (Ceph vs ZFS vs external SAN) to support ~180 TB usable capacity
ZFS with replication will be not easy to setup (lot of scripting) in bigger environments and I would generally not recommend it. You would need to have a fine grained ZFS replication setup or 180 TB on each node, which is totally unpractical. Go with a KISS solution.
The easiest method would be a SAN with Proxmox VE support so that you have ALL features you need. This is ESSENTIAL. I've never seen BlockBridge in action myself, but read only good things about it. Don't use a storage with just LVM integration.
If you go with CEPH, you would need to have as fast network as possible with that amount of space. I would recommend multiple 100 Gb connections or faster. Local storage should be NVMe and you will easily outperform one 100 Gb with a recent PCIe 5.0 card.
Assuming your 180 TB need with default 3 copies in CEPH 540 TB in total, so having in 9 nodes 540 / 9 = 60 TB, which are roughly at least 8x7,68 TB SSDs.