Best architecture for running 50+ VDSs each with its own Proxmox VE on a large Dedicated Server (2 TB RAM)

t is okay offering, i see there is financial reason for it.
This is how I look at it.

You are offering to operate a bus for people. but instead of selling seats, you are putting busses inside your bus.

Whats the use case?! If you're trying to offer a customer resources that they can distribute between disparate vms, thats simple enough to do WITHOUT that additional complexity (hint- thats what ALL vps providers already do.)
 
3 Physical Nodes (Bare Metal Hosts)
Each node runs Proxmox VE
────────────────────────────────────────────────────────

[Node 1 - Physical Proxmox]
├─ VPS1 (Proxmox VE) ───────────────┐
├─ VPS2 (Proxmox VE) ───────────────┐
├─ VPS3 (Proxmox VE) ───────────────┐
├─ VPS4 (Proxmox VE)
├─ VPS5 (Proxmox VE)
├─ VPS6 (Proxmox VE)
├─ VPS7 (Proxmox VE)
├─ VPS8 (Proxmox VE)
├─ VPS9 (Proxmox VE)
└─ VPS10 (Proxmox VE)

[Node 2 - Physical Proxmox]
├─ VPS1 (Proxmox VE) ───────────────┼──► Cluster A (Replication)
├─ VPS2 (Proxmox VE) ───────────────┼──► Cluster B (Replication)
├─ VPS3 (Proxmox VE) ───────────────┼──► Cluster C (Replication)
├─ VPS4 (Proxmox VE)
├─ VPS5 (Proxmox VE)
├─ VPS6 (Proxmox VE)
├─ VPS7 (Proxmox VE)
├─ VPS8 (Proxmox VE)
├─ VPS9 (Proxmox VE)
└─ VPS10 (Proxmox VE)

[Node 3 - Physical Proxmox]
├─ VPS1 (Proxmox VE) ───────────────┘
├─ VPS2 (Proxmox VE) ───────────────┘
├─ VPS3 (Proxmox VE) ───────────────┘
├─ VPS4 (Proxmox VE)
├─ VPS5 (Proxmox VE)
├─ VPS6 (Proxmox VE)
├─ VPS7 (Proxmox VE)
├─ VPS8 (Proxmox VE)
├─ VPS9 (Proxmox VE)
└─ VPS10 (Proxmox VE)



Each VPS (1–10) runs its own Proxmox VE instance.
VPS1 from Node1/Node2/Node3 forms a 3-node Proxmox cluster (replication only).
Same applies to VPS2, VPS3, etc.
No Ceph, virtual environments only.
 
@alexskysilk The goal is to give each customer a Proxmox environment that is as isolated as possible from the underlying physical nodes, not a shared VPS-style setup.