I have followed the guide:
https://forum.proxmox.com/threads/how-to-integrate-eset-antivirus-with-pmg.49788/post-232199
https://forum.proxmox.com/threads/pmg-6-1-how-to-add-antivirus.67006/#post-320192
Since implementing ESET, my average processing time has almost tripled on the same hardware...