I have a similar issue, - enough resources, 1.5TB of RAM, more than 500G Free RAM, all 15TB NVME Enterprise drives in CEPH, enough free space etc...
VM 1023 qmp command 'query-status' failed - got timeout
INFO: include disk 'scsi0' 'RBDNVME:vm-1023-disk-0' 400G
INFO: backup mode: snapshot...