Great
I had similar problems, Asus X99-E motherboard, Nvidia RTX2080ti and 3070 graphics cards, everything worked fine, until I restarted the host after the upgrade and dmesg log was filled with:
[ 1953.114004] vfio-pci 0000:05:00.0: BAR 3: can't reserve [mem 0xb0000000-0xb1ffffff 64bit pref]...