I have done what you are describing before, on two separate builds (office machines for me and my partner and me), and while they were successful in having a NAS as well as 2 workstations "built" within a single computer tower. There were some...
I have not yet had to replace a disk in either of my machines using encrypted boot disks. For updates, they have also worked without issues.
@LnxBil - I don't use replication on my systems, as I either use a network-based share or Ceph for my...