How do you want to use it?
In case you want a LVM, LVM-thin, ZFS or Directory (ontop of ext4?) storage you can use the webUI under "Datacenter -> YourNode -> Disks -> LVM/LVM-thin/ZFS/Directory -> "Create: ..." button". This will partition your empty disk and create the selected storage type.
Otherwise you would have to partition and format it yourself using the CLI.
Edit: Got your question wrong. If you are sure there is no data on that disk you want to keep you can wipe it using the webUI: "Datacenter -> YourNode -> Disks -> select the disk you want to wipe -> Wipe button". But according to your screenshot this wipe button is missing, it it looks like you are running a outdated PVE version where the wipe button wasn't added yet. So you either could upgrade your PVE to a more recent version or use the CLI with commands like fdisk, parted, sgdisk and so on to remove all partitions or overwrite the partition table.