Oh I see. I thought it was just the placeholder disk you get when you remove the main/only/last disk from a KVM, but it's a real disk, sorry.
There are some results for searching Google.com for "windows 2012 r2 Inaccessible Boot Device". Some complaints are due to windows updates.
This is a vmware discussion on reddit:
https://www.reddit.com/r/vmware/comments/2ama2d/vm_issues_server_2012_blue_screens_inaccessible/. OP solved the issue by:
"Fixed by changing the SCSI controller from LSI Logic SAS to LSI Logic Parallel..."
Also was there any changes made to the SCSI controller in Options tab? I see you have virtio there.
My only disk on my windows server is a virtio0 which holds the OS. Initially, I've had the default LSI xxx scsci controller type. I've swapped it to virtio and just rebooted the VM after that. The VM booted up without any issues.
Your best bet is to find out which update were applied and search for possible issues it could have caused on google.com. Next might be trying to change the SCSI controller in Options tab to see if a different boots the VM up.
I know I had to mess with SCSI controller in Proxmox 4 to have Reactos 0.4(Windows XP open source imitation) recognize the install disks.
You could also try to hammer F8 while your windows VM boots. You might find some help or clues there. That's the rescue area of windows iirc. Never mind hitting F8 does nothing in the browser. It once or twice saved my windows 7 PC some years ago.
Finally, I'd try to back it up and import it to a new VM. Also copy over your SMBIOS settings uuid if you do that as Windows will deactivate itself with a new uuid.
I don't know anything else to say, what this is what I'd try.